monoclonal antibodies (mabs) aa3 (Biogen Inc)
90
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Biogen Inc
monoclonal antibodies (mabs) aa3
Monoclonal Antibodies (Mabs) Aa3, supplied by Biogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/monoclonal+antibodies+(mabs)+aa3/monoclonal+antibodies++mabs++aa3/pmc02725717-59-12-16
Average 90 stars, based on 1 article reviews
Monoclonal Antibodies (Mabs) Aa3, supplied by Biogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/monoclonal+antibodies+(mabs)+aa3/monoclonal+antibodies++mabs++aa3/pmc02725717-59-12-16
Average 90 stars, based on 1 article reviews
monoclonal antibodies (mabs) aa3 - by Bioz Stars,
2026-10
90/100 stars
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1) Product Images from "Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities ▿ "
Article Title: Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities
Journal:
doi: 10.1128/MCB.01808-08
Figure Legend Snippet: (A) Graphic representation of the relative antiproliferative potencies of IFN-α2 and IFN-β in the human cell lines 2fTGH (fibrosarcoma), WISH (amniotic), MDA231 (breast cancer), and Daudi (B lymphoma) and the three U5-derived clones (U5-low/low, U5-low/hi, and U5-hi/hi) described in this study. EC50s (pM) for IFN-α2 are plotted against the ratio of the EC50 of IFN-α2 to that of IFN-β for each cell line (Table (Table1).1). (B) Levels of IFNAR1 and IFNAR2 in the three U5-derived clones (U5-low/low, U5-low/hi, and U5-hi/hi) and in the parental 2fTGH cells. Surface IFNAR1 and IFNAR2 were quantified by FACS analysis using MAbs AA3 and CD118, respectively. Dark gray area, isotypic control; light gray area, 2fTGH; black line, U5-low/low, U5-low/hi, or U5-hi/hi. Of note, these clones exhibited similar forward scatter values, as determined by FACS analysis, indicating that the increases observed are due to changes in surface receptor density and not cell volume. (C) Analysis of the expression level of Jak/Stat pathway components in 2fTGH cells and the U5-derived clones. Total cell lysates (30 μg) were analyzed by Western blotting with the indicated Abs. Loading was evaluated by measuring Akt levels.
Techniques Used: Derivative Assay, Clone Assay, Expressing, Western Blot
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